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    科研團隊
    當前位置: 首頁>>科學研究>>科研團隊>>正文
    空間及特殊環境骨骼系統健康科學與工程研究室
      審核人:

    團隊簡介

    學科帶頭人:商澎(教授 博導)

    成員:楊鵬飛副教授  任麗副教授  呼延霆助理教授  呂歡歡助理教授  苑曦宸助理教授  韓煒博士后  楊建成博士后

     

    團隊現有人員35人,其中教授1名,副教授2名,助理教授3名,博士后2名,在讀博士生14名,在讀碩士生13名,是一支年輕進取、富有活力的科研團隊。

    聯系人:商澎,電話:029-88460391,E-mail:shangpeng@nwpu.edu.cn

    研究方向

     

    一、 空間及特殊環境生物學

    1. 圍繞“骨質流失”的生理現象,從機體整體、組織、細胞分子等多個層次,研究空間環境對肌肉骨骼系統的影響和作用機制,著重探討空間環境中的復合物理環境對骨骨源細胞結構功能的影響及作用機理;

    2. 研究重力因素對擬南芥等植物的生物學效應及其機制;

     

    二、 磁生物學

    1. 研究組織及細胞的電磁特性;

    2. 探討不同強度靜磁場(亞磁場、中等強度磁場及強磁場)調控細胞生理過程的作用機制;

     

    三、 多尺度生物力學與力生物學

    從超微觀、微觀及宏觀等多尺度、跨層次研究骨、關節及肌肉的力學性能及其響應外界力學環境的變化過程和生物力學機制。

     

    近兩年代表性論文

    1. Xu H, Ning D, Zhao D, Chen Y, Zhao D, Gu S, Jiang JX, Shang P*. Blockage of hemichannels alters gene expression in osteocytes in a high magneto-gravitational environment. Front Biosci (Landmark Ed). 2017, 22:783-794.

    2. Xu H, Liu R, Ning D, Zhang J, Yang R, Riquelme MA, Li J, Jiang JX*, Shang P*. Biological Responses of Osteocytic Connexin 43 Hemichannels to Simulated Microgravity. J Orthepedic Res, 2016, 23224.

    3. Ren Li, Wang Zhe, Huang Ling Wei, Yang PengFei, Shang Peng. Technologies for strain assessment from whole bone to mineralized osteoid level: a critical review. Journal of Mechanics in Medicine and Biology. 16: 1630002. 2016.

    4. Li Chenrui, Wang Qian, Ren Tianjing, Zhang Yufeng, Christopher Wai Kei Lam, Moses S.S. Chow, Zuo Zhong. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. Journal of Pharmaceutical and Biomedical Analysis. 128: 286-293. 2016.

    5. Li Ren, Peng-Fei Yang,Zhe Wang, Jian Zhang, Chong Ding, Peng Shang*. Biomechanical and biophysicalenvironment of bone from the macroscopic to the pericellular and molecularlevel. Journal of the Mechanical Behavior of Biomedical Materials,2015, 50, 104-122.

    6. Ling-Wei Huang, Li Ren,Peng-Fei Yang, Peng Shang*. Response of osteoblasts to the stimulus of fluid flow.CriticalReview in Eukaryotic Gene Expression, 2015, 25(2): 153-162.

    7. Peng-Fei Yang, AndreasKriechbaumer, Kirsten Albracht, Maximilian Sanno, Bergita Ganse, Timmo Koy,Peng Shang, Gert-Peter Brüggemann, Lars Peter Müller, J rn Rittweger*. On therelationship between tibia deformation and regional muscle contractions inhumans in vivo. Journal of Biomechanics,2015, 48(3): 456-464.

    8. Yi Lv, Peng Shang*. Anilluminated growth system for the study of Arabidopsis thaliana duringdiamagnetic levitation by a superconducting magnet. Advance in Space Research, 2015, 55(1): 525-533.

    9. Jian Zhang, Yong Zhao*,Peng Shang*. Responds of bone cells to microgravity: ground-based research, MicrogravityScience and Technology. 2015, 27(6): 455-464.

    10. Hui Chen, Yong Zhao*,Peng Shang*. The distinctive sensitivity to microgravity of immune cell subpopulations,MicrogravityScience and Technology. 2015,27(6): 1-10.

    11. Chong-Zhen Wang, PengShang*, Yong Zhao*. Microgravity activates p38 MAPK-C/EBPβ pathway to regulatethe expression of arginase and inflammatory cytokines in macrophages. InflammationResearch, 2015, 64: 301-311.

    12. Yang Wang, Peng Shang*,Air-Rong Qian*. GeneChip expression profiling reveals the alterations of energymetabolism related genes in osteocytes under large gradient high magneticfields.PLoS One, 2015, 10(1):e0116359.

    13. Li-Fang Hu, Peng Shang*.Mineralization initiation of MC3T3-E1 preosteoblast is suppressed undersimulated microgravity condition. Cell Biology International, 2015, 39(4): 364-372.

    14. Hui-Yun Xu, Sumin Gu,Manuel A. Riquelme, Sirisha Burra, Danielle Callaway, Hong-Yun Cheng, TejaGuda, James Schmitz, Roberto J. Fajardo, Sherry L. Werner, Hong Zhao, PengShang, Mark L. Johnson, Lynda F. Bonewald, Jean X. Jiang*. Connexin 43 channelsare essential for normal bone structure and osteocyte viability.Journalof Bone and Mineral Research, 2015, 30(3): 436-448.

    15. Yu-Long Sun, Zhi-Hao Chen,Xiao-Hu Chen, Chong Yin, Di-Jie Li, Xiao-Li Ma, Fan Zhao, Ge Zhang, Peng Shang,Ai-Rong Qian. Diamagnetic levitation promotes osteoclast differentiation fromRAW264.7 cells.IEEE Transactions on Biomedical Engineering, 2015, 62(3):900-8.

    16. Yu-Long Sun, Xiaohu Chen,Zhihao Chen, Xiaoli Ma, Dijie Li, Peng Shang, Ai-Rong Qian*. Neuropeptide FFattenuates RANKL-induced differentiation of RAW264.7 cells into osteoclast-likecells. Archives of Oral Biology, 60:282-292, 2015.

     

     

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